《在欧邦人からの情報》
Wladimir Werteleckiの報告．
（ウクライナのポレーシア地方とその近隣の低汚染地域での奇形児の発生頻度を比較した論文）
チェルノブイリの慢性的な低線量放射線に被爆したウクライナのRivne県（サハリン州の北半分を表す領域）のPolissia地域、ここでの奇形の発生例や病気の原因，人口率を報告した．
2000年から2006年の期間に，Rivneの残りの地域とPOLISSI地域を比較して（96438人の出生の中で）奇形の統計的分析をした．
結果はRivne県の神経管欠損は（10 000人出生当たり22.2人）、ヨーロッパで最高である．
結合体双生児と奇形の発生率も上昇している． Polissia地域では、神経管欠損の全体的な率は高く，小頭症と眼球疾病症も上昇する可能性がある．
この結果は、ウクライナの慢性的な低線量放射線影響地域における奇形の調査を継続するのに十分な説得力がある．
以上です．
☆Malformations in a Chornobyl-Impacted Region
（Wladimir Wertelecki, MD）
http://pediatrics.aappublications.org/content/125/4/e836.full
OBJECTIVE: One of the populations most exposed to chronic low-dose radiation from Chornobyl (Chernobyl in Russian) lives in Polissia, the region representing the northern half of Rivne Province (Oblast) in Ukraine. Here the patterns and population rates of malformations are reported and possible etiologic factors and regional contrasts are explored.
PATIENTS AND METHODS: Malformations, as defined by international standards, noted among all 96 438 births in Rivne between 2000 and 2006, were analyzed statistically. Contrasts of rates in Polissia compared with the rest of Rivne also were investigated.
RESULTS: The overall rate of neural tube defects in Rivne is among the highest in Europe (22.2 per 10 000 live births). The rates of conjoined twins and teratomas also seem to be elevated. In Polissia, the overall rates of neural tube defects are even higher (27.0 vs 18.3, respectively; odds ratio: 1.46 [95% confidence interval: 1.13–1.93]), and the rates of microcephaly and microphthalmia may also be elevated.
CONCLUSIONS: The malformation patterns observed suggest early disruptions of blastogenesis, manifesting as alterations of body axes, twinning, duplications, laterality, and midline formation. The results are sufficiently compelling to justify continuing and expanding this investigation of malformations in chronic low-dose radiation-impacted regions of Ukraine.
